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. 1967 Sep 1;157(3792):1060-2.
doi: 10.1126/science.157.3792.1060.

Cytotoxic effect of lymphocyte-antigen interaction in delayed hypersensitivity

N H Ruddle, B H Waksman

Cytotoxic effect of lymphocyte-antigen interaction in delayed hypersensitivity

N H Ruddle et al. Science. .

Abstract

Lymph node cells from inbred rats having delayed sensitivity to soluble proteins inhibit growth of syngeneic or allogeneic fibroblasts in the presence of specific antigen. A relation is suggested between this in vitro phenomenon and other systems believed to be specific manifestations of delayed hypersensitivity.

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