Serotonin release from brain slices by electrical stimulation: regional differences and effect of LSD
- PMID: 6037863
- DOI: 10.1126/science.157.3795.1461
Serotonin release from brain slices by electrical stimulation: regional differences and effect of LSD
Abstract
Slices of rat brain which had accumulated tritiated serotonin either in vivo or in vitro were superfused and electrically stimulated. There occurred a marked release of the exogenous amine and, to a lesser extent, its deaminated metabolites, which varied with the region of brain tested and was inhibited by lysergic acid diethylamide.
Similar articles
-
A simple organ bath for electrical stimulation and superfusion of rat brain slices.J Pharmacol Methods. 1986 Nov;16(3):185-99. doi: 10.1016/0160-5402(86)90041-0. J Pharmacol Methods. 1986. PMID: 3784567
-
Release of [3H]serotonin from brain slices.J Neurochem. 1969 Apr;16(4):607-15. doi: 10.1111/j.1471-4159.1969.tb06860.x. J Neurochem. 1969. PMID: 5768216 No abstract available.
-
Effects of lysergic acid diethylamide on the uptake and retention of brain 5-hydroxytryptamine in vivo and in vitro.Biochem Pharmacol. 1973 Sep 1;22(17):2183-93. doi: 10.1016/0006-2952(73)90117-2. Biochem Pharmacol. 1973. PMID: 4270151 No abstract available.
-
Regional differences in accumulation of tritium-labeled norepinephrine, 5-hydroxytryptamine and gamma-aminobutyric acid in brain slices of spider and rhesus monkey.Brain Res. 1969 Dec;16(2):469-77. doi: 10.1016/0006-8993(69)90239-x. Brain Res. 1969. PMID: 4982784 No abstract available.
-
Chronic lysergic acid diethylamide administration and serotonin turnover in various regions of the rat brain.J Neurochem. 1974 Oct;23(4):625-8. doi: 10.1111/j.1471-4159.1974.tb04384.x. J Neurochem. 1974. PMID: 4430908 No abstract available.
Cited by
-
Antagonism of 5-hydroxytryptamine by LSD 25 in the central nervous system: a possible neuronal basis for the actions of LSD 25.Br J Pharmacol. 1970 Oct;40(2):202-18. doi: 10.1111/j.1476-5381.1970.tb09914.x. Br J Pharmacol. 1970. PMID: 5492893 Free PMC article.
-
Effects of para-methoxyamphetamine and 2,5-dimethoxyamphetamine on serotonergic mechanisms.Naunyn Schmiedebergs Arch Pharmacol. 1978 Sep;304(2):101-5. doi: 10.1007/BF00495545. Naunyn Schmiedebergs Arch Pharmacol. 1978. PMID: 581302
-
The effect of electrical stimulation, light and amino acids on the efflux of 35S-taurine from the retina of domestic fowl.Exp Brain Res. 1974 Jan 31;19(2):131-41. doi: 10.1007/BF00238530. Exp Brain Res. 1974. PMID: 4361032 No abstract available.
-
Some neuropharmacological aspects of schizophrenia: a short review.Ir J Med Sci. 1978 Aug;147 Suppl 1:43-8. doi: 10.1007/BF02947903. Ir J Med Sci. 1978. PMID: 567632 No abstract available.
-
Electroconvulsive shock increases the behavioural responses of rats to brain 5-hydroxytryptamine accumulation and central nervous system stimulant drugs.Br J Pharmacol. 1976 Feb;56(2):193-9. doi: 10.1111/j.1476-5381.1976.tb07442.x. Br J Pharmacol. 1976. PMID: 3248 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources