doi: 10.1126/science.158.3800.512.
Antigenic competition: cellular or humoral
- PMID: 6048110
- DOI: 10.1126/science.158.3800.512
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Antigenic competition: cellular or humoral
Science.
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Abstract
The injection of one antigen into mice inhibited the response to a second when 1 to 10 days separated the two injections. When the same type of inhibition was attempted in gamma-irradiated mice reconstituted with normal spleen cells, the inhibition was greater in mice receiving 50 million spleen cells than in those receiving 10 million. The results are interpreted as favoring a humoral mechanism of inhibition.
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