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. 1967 Jun;103(3):791-5.
doi: 10.1042/bj1030791.

[35S]thiosulphate oxidation by rat liver mitochondria in the presence of glutathione

A Koj, J Frendo, Z Janik

[35S]thiosulphate oxidation by rat liver mitochondria in the presence of glutathione

A Koj et al. Biochem J. 1967 Jun.

Abstract

1. Rat liver mitochondria incubated in oxygen with glutathione and [(35)S]-thiosulphate produced labelled sulphate. 2. Inner-labelled thiosulphate (S.(35)SO(3))(2-) was converted into [(35)S]sulphate more rapidly than outer-labelled thiosulphate ((35)S.SO(3))(2-). 3. Thiosulphate labelled in both sulphur atoms was formed during ((35)S.SO(3))(2-) oxidation; the outer sulphur atom before oxidation to sulphate was incorporated into the inner position. 4. A thiosulphate cycle in the metabolic pathway of sulphate formation in animal tissues is discussed.

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