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. 1967 Oct 13;158(3798):272-4.
doi: 10.1126/science.158.3798.272.

Regeneration of rat liver: transfer of humoral agent by cross circulation

Regeneration of rat liver: transfer of humoral agent by cross circulation

F L Moolten et al. Science. .

Abstract

Carotid-to-jugular cross circulation between partially hepatectomized and normal rats, via polyethylene cannulas, stimulated incorporation of (14)C-thymidine into hepatic DNA in the normal partners when it was maintained for 19 hours at a flow rate of about 2 milliliters per minute. Cross circulation for 7 hours or less was ineffective.

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