doi: 10.1016/s0140-6736(76)92592-7.
Oestrogen receptors in human malignant melanoma
- PMID: 60569
- DOI: 10.1016/s0140-6736(76)92592-7
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Oestrogen receptors in human malignant melanoma
Lancet.
.
Abstract
16 of 35 patients (46%) with malignant melanoma were found to have cytoplasmic oestrogen-receptor activity in biopsy specimens. OEstrogen-receptor activity was detected in primary lesions, lymph-node metastases, skin metastases, and visceral metastases. Equal percentages of males and females had positive assays. Scatchard analysis of binding in one case was consistent with a single class of high affinity receptor sites.
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