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. 1967 Dec 22;158(3808):1600-1.
doi: 10.1126/science.158.3808.1600.

Actinomycin D blocks formation of memory of shock-avoidance in goldfish

B W Agranoff, R E Davis, L Casola, R Lim

Actinomycin D blocks formation of memory of shock-avoidance in goldfish

B W Agranoff et al. Science. .

Abstract

When 2 micrograms of antinomycin D was injected intracranially into goldfish immediately after a training session, the formation of long-term memory of a shock-avoidance was blocked. The results are discussed in relation to similar findings with acetoxycycloheximide and puromycin in the goldfish and with apparently conflicting results in the mouse.

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