The molecular weight range of nematode allergens
Abstract
Gel-filtration on Sephadex, of Ascaris, Nippostrongylus, Toxocara and Toxascaris antigens revealed that the allergenic components had a molecular weight range of 10,000–50,000. Allergenicity was assessed by homologous passive cutaneous anaphylaxis, to detect reagins in man and reagin-like antibodies in the rat and rabbit. It is suggested that nematodes can provoke a Type I allergic reaction in man, rat and the rabbit.
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