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. 1967 Nov;13(5):535-7.

The molecular weight range of nematode allergens

R S Hogarth-Scott

The molecular weight range of nematode allergens

R S Hogarth-Scott. Immunology. 1967 Nov.

Abstract

Gel-filtration on Sephadex, of Ascaris, Nippostrongylus, Toxocara and Toxascaris antigens revealed that the allergenic components had a molecular weight range of 10,000–50,000. Allergenicity was assessed by homologous passive cutaneous anaphylaxis, to detect reagins in man and reagin-like antibodies in the rat and rabbit. It is suggested that nematodes can provoke a Type I allergic reaction in man, rat and the rabbit.

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References

    1. Immunology. 1967 Feb;12(2):113-31 - PubMed
    1. Nature. 1964 Oct 3;204:91-2 - PubMed

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