Review
doi: 10.1016/0264-410x(84)90081-1.
New poliovirus vaccines: a molecular approach
- PMID: 6085198
- DOI: 10.1016/0264-410x(84)90081-1
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Review
New poliovirus vaccines: a molecular approach
Vaccine.
1984 Sep.
Abstract
This article summarizes recent work on the determinants of antigenicity in poliovirus type 3 and reports on experiments in progress aimed at understanding the molecular basis of attenuation in Sabin's type 3 vaccines. Ways in which this new information might be used to produce alternative, safe, inexpensive, multivalent vaccines against polio and other enteroviruses are discussed.
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