Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1984;67(1):6-17.
doi: 10.1007/BF00270551.

Localisation of the Becker muscular dystrophy gene on the short arm of the X chromosome by linkage to cloned DNA sequences

H M Kingston, M Sarfarazi, N S Thomas, P S Harper

Localisation of the Becker muscular dystrophy gene on the short arm of the X chromosome by linkage to cloned DNA sequences

H M Kingston et al. Hum Genet. 1984.

Abstract

A linkage study in 30 Becker muscular dystrophy (BMD) kindreds using three cloned DNA sequences from the X chromosome which demonstrate restriction fragment length polymorphisms (RFLPs), suggests that the BMD gene is located on the short arm of the X chromosome, in the p21 region. The genes for Becker and Duchenne dystrophies must therefore be closely linked, if not allelic, and any future DNA probes found to be of practical use in one disorder should be equally applicable to the other. The linkage analysis also provides data on the frequency of recombination along the short arm of the X chromosome, and across the centromeric region.

PubMed Disclaimer

References

    1. Am J Hum Genet. 1974 Sep;26(5):588-97 - PubMed
    1. Hum Hered. 1975;25(2):95-105 - PubMed
    1. Proc Natl Acad Sci U S A. 1977 Mar;74(3):1245-9 - PubMed
    1. J Med Genet. 1983 Aug;20(4):255-8 - PubMed
    1. J Med Genet. 1974 Dec;11(4):321-7 - PubMed

Publication types

LinkOut - more resources