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. 1984 Jul:65 ( Pt 7):1225-8.
doi: 10.1099/0022-1317-65-7-1225.

Early virion-associated suppression of cellular protein synthesis by herpes simplex virus is accompanied by inactivation of mRNA

M L Fenwick, M M McMenamin

Early virion-associated suppression of cellular protein synthesis by herpes simplex virus is accompanied by inactivation of mRNA

M L Fenwick et al. J Gen Virol. 1984 Jul.

Abstract

Vero cells infected with herpes simplex virus in the presence of actinomycin or cycloheximide, or with u.v.-inactivated virus, suffered a rapid loss of functional mRNA as determined by translation in vitro. It is suggested that a virion-associated factor causes a structural change in the mRNA of the host cell.

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