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. 1984 Jul 25;12(14):5627-38.
doi: 10.1093/nar/12.14.5627.

The use of heparin as a simple cost-effective means of controlling background in nucleic acid hybridization procedures

L Singh, K W Jones
Free PMC article

The use of heparin as a simple cost-effective means of controlling background in nucleic acid hybridization procedures

L Singh et al. Nucleic Acids Res. .
Free PMC article

Abstract

The use of heparin as a simple, effective and cheap substitute for conventional methods of controlling background in hybridization procedures is described and illustrated with reference to the use of DNA probes in filter and in situ hybridization. Possible specific mechanisms for this heparin effect are discussed.

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