Restriction analysis and homology studies of the bovine adenovirus 7 genome
- PMID: 6088811
- PMCID: PMC255860
- DOI: 10.1128/JVI.51.3.880-883.1984
Restriction analysis and homology studies of the bovine adenovirus 7 genome
Abstract
We located the cleavage sites for restriction endonucleases EcoRI, HindIII, and BamHI on the genome of bovine adenovirus 7. Cross-hybridization at reduced stringency revealed two regions of homology shared by the DNA of human adenovirus 2 and bovine adenoviruses 7 and 3. These regions correspond to the hexon and the IVa2 protein genes of the human adenovirus. Another region of homology shared only by the human adenovirus and bovine adenovirus 7 corresponded to the penton or the polypeptide IIIa genes. These results allowed us to align the restriction map of bovine adenovirus 7 with respect to the other adenoviruses.
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