Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1984 Aug;310(5979):650-5.
doi: 10.1038/310650a0.

Organization and evolution of the class I gene family in the major histocompatibility complex of the C57BL/10 mouse

E H Weiss, L Golden, K Fahrner, A L Mellor, J J Devlin, H Bullman, H Tiddens, H Bud, R A Flavell
Comparative Study

Organization and evolution of the class I gene family in the major histocompatibility complex of the C57BL/10 mouse

E H Weiss et al. Nature. 1984 Aug.

Abstract

The major histocompatibility complex (MHC) encodes several classes of protein vital to the regulation of the immune response. We have isolated 26 class I genes that map to this region in the C57BL/10 mouse and linked these into three gene clusters. The number of genes differs from the number found in the BALB/c strain and comparison of the organization of the class I genes in these two strains shows conserved regions and polymorphic regions which probably result from deletions, insertions and translocations within the MHC.

PubMed Disclaimer

Publication types