Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1984;311(5984):350-5.
doi: 10.1038/311350a0.

Apparent discontinuous transcription of Trypanosoma brucei variant surface antigen genes

D A Campbell, D A Thornton, J C Boothroyd

Apparent discontinuous transcription of Trypanosoma brucei variant surface antigen genes

D A Campbell et al. Nature. 1984.

Abstract

The repeated mini-exon sequence that encodes the first 35 base pairs of all variant surface antigen mRNAs of Trypanosoma brucei directs the synthesis of a discrete 137-nucleotide transcript. It thus seems that variant surface antigen mRNAs are transcribed discontinuously, and we present two alternative models for how this might occur.

PubMed Disclaimer

References

    1. Cross GAM, Holder AA, Allen GA, Boothroyd JC. Am. J. trop. Med. Hyg. 1980;29:393–417. doi: 10.4269/ajtmh.1980.29.393. - DOI - PubMed
    1. Englund PT, Hajduk SL, Narini JC. A. Rev. Biochem. 1982;51:695–726. doi: 10.1146/annurev.bi.51.070182.003403. - DOI - PubMed
    1. Borst P, Cross GAM. Cell. 1982;29:291–303. doi: 10.1016/0092-8674(82)90146-5. - DOI - PubMed
    1. Pays E, Lheureux M, Steinert M. Nature. 1981;292:265–267. doi: 10.1038/292265a0. - DOI - PubMed
    1. Hoeijmakers JHJ, Borst P, Van den Burg J, Weissmann C, Cross GAM. Gene. 1980;8:391–417. doi: 10.1016/0378-1119(80)90043-8. - DOI - PubMed

Publication types

Substances

Associated data