doi: 10.1073/pnas.81.18.5792.
Processing of complex heteroduplexes in Escherichia coli and Cos-1 monkey cells
- PMID: 6091108
- PMCID: PMC391797
- DOI: 10.1073/pnas.81.18.5792
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Processing of complex heteroduplexes in Escherichia coli and Cos-1 monkey cells
Proc Natl Acad Sci U S A.
1984 Sep.
Abstract
Upon transformation into Escherichia coli or Cos-1 monkey cells, heteroduplex DNA made of two sequences containing many nucleotide mismatches yields a wide array of different molecules, some with a patchwork structure. Thus, complex heteroduplexes can be processed to generate many genetic variants.
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