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. 1984 Oct 12;226(4671):177-9.
doi: 10.1126/science.6091270.

Expression of the 3' terminal region of human T-cell leukemia viruses

W Wachsman, K Shimotohno, S C Clark, D W Golde, I S Chen

Expression of the 3' terminal region of human T-cell leukemia viruses

W Wachsman et al. Science. .

Abstract

Human T-cell leukemia viruses (HTLV) are closely associated with some human T-cell leukemias and lymphomas. A unique 3' region of the HTLV genome is believed to be involved in HTLV-induced cellular transformation, although the function of this region has yet to be determined. A subgenomic messenger RNA transcribed from this region of HTLV has now been characterized. These results provide direct evidence for the expression of a novel gene in HTLV.

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