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. 1984 Oct;38(3):737-44.
doi: 10.1016/0092-8674(84)90269-1.

Termination of transcription in the mouse alpha-amylase gene Amy-2a occurs at multiple sites downstream of the polyadenylation site

O Hagenbüchle, P K Wellauer, D L Cribbs, U Schibler

Termination of transcription in the mouse alpha-amylase gene Amy-2a occurs at multiple sites downstream of the polyadenylation site

O Hagenbüchle et al. Cell. 1984 Oct.

Abstract

We have delimited the region of transcription termination in the alpha-amylase gene Amy-2a. Mapping of in vitro elongated nascent transcripts to Amy-2a restriction fragments indicates that transcription terminates in a region between 2.5 and 4 kb downstream of the polyadenylation site. These runoff transcription experiments, combined with S1 nuclease mapping of nuclear transcripts at steady state, suggest that transcription termination occurs at multiple sites.

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