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Comparative Study
. 1984 Oct 30;138(2):347-52.
doi: 10.1016/0042-6822(84)90359-3.

Sequence homology between the large tumor antigen of polyoma viruses and the putative E1 protein of papilloma viruses

I Seif
Comparative Study

Sequence homology between the large tumor antigen of polyoma viruses and the putative E1 protein of papilloma viruses

I Seif. Virology. .

Abstract

The large tumor antigen of simian virus 40, mouse polyoma virus, and human BK virus is compared to the E1 protein of human and bovine papilloma viruses. It is suggested that large T and E1 are evolutionarily related and that the region of major homology forms part of an alpha/beta domain involved in nucleotide binding.

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