doi: 10.1038/312242a0.
Polyoma virus DNA replication requires an enhancer
- PMID: 6095089
- DOI: 10.1038/312242a0
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Polyoma virus DNA replication requires an enhancer
Nature.
1984 Nov.
Abstract
Sequences which activate polyoma virus DNA replication are located within a region that also includes the transcriptional enhancer. We demonstrate a cis involvement of enhancers in DNA replication by showing that this region can be replaced by other enhancers, in a position- and orientation-independent manner, and that an immunoglobulin gene enhancer confers tissue-specific replicatory ability.
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