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. 1984 Dec;312(5995):608-12.
doi: 10.1038/312608a0.

Adenovirus-2 E1A products repress enhancer-induced stimulation of transcription

E Borrelli, R Hen, P Chambon

Adenovirus-2 E1A products repress enhancer-induced stimulation of transcription

E Borrelli et al. Nature. 1984 Dec.

Abstract

The adenovirus-2 early region 1A (E1A) products repress activation of transcription induced by the simian virus 40, polyoma virus and adenovirus-2 E1A enhancers. The repression probably involves an interaction between the enhancer elements and a trans-acting factor(s), possibly the E1A products themselves.

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