Primary structure and genomic organization of the histidine-rich protein of the malaria parasite Plasmodium lophurae
- PMID: 6095114
- DOI: 10.1038/312616a0
Primary structure and genomic organization of the histidine-rich protein of the malaria parasite Plasmodium lophurae
Abstract
The nucleotide sequence of a complete genomic clone for the histidine-rich protein of Plasmodium lophurae has been determined. The deduced amino acid sequence of the mature protein shows numerous tandemly repeated units preceded by a signal and a pro peptide. The gene is interrupted by an intron with a separate exon coding for the signal peptide. The signal peptide-encoding exon detects multiple cross-hybridizing sequences in the parasite genome.
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