Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1984;9(10):439-42.
doi: 10.1007/BF00563165.

Is the relative 99mTc-DMSA clearance a useful marker of proximal tubular dysfunction?

W H van Luijk, G J Ensing, S Meijer, A J Donker, D A Piers
Comparative Study

Is the relative 99mTc-DMSA clearance a useful marker of proximal tubular dysfunction?

W H van Luijk et al. Eur J Nucl Med. 1984.

Abstract

The clearance of 125I-sodium iothalamate, 131I-sodium hippurate, 99mTc-DMSA, and beta 2-microglobulin were determined in 20 patients with proven or suspected proximal tubular dysfunction and in 18 control patients with various renal diseases. A clear distinction in the relative 99mTc-DMSA clearance was observed between patients with proximal tubulopathy (14%-35%) and control patients (less than 14%). A similar difference between the two groups was found in the relative beta 2-microglobulin clearance. Nine patients with proximal tubulopathy showed an elevated filtration fraction versus only two control patients. The renal handling of 99mTc-DMSA seems to be an indicator of proximal tubular function.

PubMed Disclaimer

References

    1. Eur J Nucl Med. 1983;8(9):404-5 - PubMed
    1. J Nucl Med. 1981 Dec;22(12):1054-8 - PubMed
    1. Am J Med. 1977 Apr;62(4):490-6 - PubMed
    1. Nephron. 1973;10(5):320-31 - PubMed
    1. Neth J Med. 1977;20(3):97-103 - PubMed

Publication types

MeSH terms

LinkOut - more resources