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. 1984 Dec 10;178(2):187-92.
doi: 10.1016/0014-5793(84)80598-0.

The H+/O ratio of proton translocation linked to the oxidation of succinate by mitochondria

K Krab, J Soos, M Wikström
Free article

The H+/O ratio of proton translocation linked to the oxidation of succinate by mitochondria

K Krab et al. FEBS Lett. .
Free article

Abstract

In a recent communication Lehninger and co-workers (Costa, L.E., Reynaferje, B., and Lehninger, A.L. (1984) J. Biol. Chem. 259, 4802-4811) reported values approaching 8 for the H+/O ratio of vectorial proton ejection from rat liver mitochondria respiring with succinate. Here we present a rigorous analysis of these measurements which reveals that they may significantly overestimate the true H+/O stoicheiometry.

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