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. 1984 Oct;26(4):527-34.
doi: 10.1128/AAC.26.4.527.

Itraconazole, a new triazole that is orally active in aspergillosis

J Van Cutsem, F Van Gerven, M A Van de Ven, M Borgers, P A Janssen

Itraconazole, a new triazole that is orally active in aspergillosis

J Van Cutsem et al. Antimicrob Agents Chemother. 1984 Oct.

Abstract

Itraconazole is a new orally active triazole derivative with broad-spectrum antifungal activity. This drug is effective in experimental aspergillosis and possesses in vitro activity against various species and strains of Aspergillus. Morphological destruction of inoculated hyphae and complete inhibition of hyphal outgrowth in culture is obtained from 0.07 micrograms ml-1 (10(-7)M) onward. These properties make itraconazole a likely candidate for clinical evaluation in disseminated aspergillosis.

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References

    1. Ann Intern Med. 1979 Jan;90(1):4-9 - PubMed
    1. Mykosen. 1981 Oct;24(10):596-602 - PubMed
    1. Am J Med. 1983 Jan 24;74(1B):2-8 - PubMed
    1. Am J Med. 1983 Jan 24;74(1B):9-15 - PubMed
    1. Arch Intern Med. 1977 Jun;137(6):769-71 - PubMed

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