Comparative activities of the beta-lactamase inhibitors YTR 830, sodium clavulanate, and sulbactam combined with amoxicillin or ampicillin
- PMID: 6097169
- PMCID: PMC179968
- DOI: 10.1128/AAC.26.4.580
Comparative activities of the beta-lactamase inhibitors YTR 830, sodium clavulanate, and sulbactam combined with amoxicillin or ampicillin
Abstract
YTR 830, a new beta-lactamase inhibitor, was compared with clavulanic acid and sulbactam against aminopenicillin-resistant clinical isolates. At a concentration of 8 micrograms/ml, YTR 830 was as effective as clavulanate or sulbactam in reducing the aminopenicillin MICs. Combined with amoxicillin, YTR 830 is a potentially useful agent for therapy of many bacterial infections.
Similar articles
-
Comparative activities of the beta-lactamase inhibitors YTR 830, clavulanate, and sulbactam combined with ampicillin and broad-spectrum penicillins against defined beta-lactamase-producing aerobic gram-negative bacilli.Antimicrob Agents Chemother. 1986 Jun;29(6):980-5. doi: 10.1128/AAC.29.6.980. Antimicrob Agents Chemother. 1986. PMID: 3015017 Free PMC article.
-
Comparative activity of beta-lactamase inhibitors YTR 830, clavulanate, and sulbactam combined with beta-lactams against beta-lactamase-producing anaerobes.Antimicrob Agents Chemother. 1986 Nov;30(5):789-91. doi: 10.1128/AAC.30.5.789. Antimicrob Agents Chemother. 1986. PMID: 3026241 Free PMC article.
-
Comparative in vitro and in vivo activities of piperacillin combined with the beta-lactamase inhibitors tazobactam, clavulanic acid, and sulbactam.Antimicrob Agents Chemother. 1989 Nov;33(11):1964-9. doi: 10.1128/AAC.33.11.1964. Antimicrob Agents Chemother. 1989. PMID: 2558615 Free PMC article.
-
Evolution of beta-lactamase inhibitors.Rev Infect Dis. 1991 Jul-Aug;13 Suppl 9:S727-32. doi: 10.1093/clinids/13.supplement_9.s727. Rev Infect Dis. 1991. PMID: 1656513 Review.
-
Beta-lactamase inhibitors: another approach to overcoming antimicrobial resistance.Infect Control. 1987 Jan;8(1):36-40. doi: 10.1017/s0195941700066972. Infect Control. 1987. PMID: 3028975 Review.
Cited by
-
Comparative activity of several antimicrobial agents against nosocomial Gram-negative rods isolated across Canada.Can J Infect Dis. 1995 Mar;6(2):76-82. doi: 10.1155/1995/297910. Can J Infect Dis. 1995. PMID: 22416207 Free PMC article.
-
Beta-lactamase inhibitors from laboratory to clinic.Clin Microbiol Rev. 1988 Jan;1(1):109-23. doi: 10.1128/CMR.1.1.109. Clin Microbiol Rev. 1988. PMID: 3060240 Free PMC article. Review.
-
Piperacillin-tazobactam versus imipenem-cilastatin for treatment of intra-abdominal infections.Antimicrob Agents Chemother. 1992 Dec;36(12):2766-73. doi: 10.1128/AAC.36.12.2766. Antimicrob Agents Chemother. 1992. PMID: 1336347 Free PMC article. Clinical Trial.
-
Role of the beta-lactamase of Campylobacter jejuni in resistance to beta-lactam agents.Antimicrob Agents Chemother. 1991 May;35(5):813-8. doi: 10.1128/AAC.35.5.813. Antimicrob Agents Chemother. 1991. PMID: 1854162 Free PMC article.
-
Helicobacter Pylori: A Review of Current Treatment Options in Clinical Practice.Life (Basel). 2022 Dec 6;12(12):2038. doi: 10.3390/life12122038. Life (Basel). 2022. PMID: 36556402 Free PMC article. Review.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources