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Comparative Study
. 1980 Apr 19;1(8173):851-3.
doi: 10.1016/s0140-6736(80)91356-2.

New enzyme immunoassays for measurement of influenza A/Victoria/3/75 virus in nasal washes

R A Berg, R H Yolken, S I Rennard, R Dolin, B R Murphy, S E Straus
Comparative Study

New enzyme immunoassays for measurement of influenza A/Victoria/3/75 virus in nasal washes

R A Berg et al. Lancet. .

Abstract

Nasopharyngeal (NP) washes from 12 patients experimentally infected with influenza A/Victoria/3/75 wild-type virus were tested in 2 newly developed enzyme-immunoassay (EIA) systems. Results were compared with infectivity titres of the NP wash specimens in rhesus monkey kidney-tissue culture. EIA detected A/Victoria/3/75 haemagglutinin antigen for more days than did culture. EIA is also rapid and easy to do in large numbers; hence it may have advantages over culture methods for the diagnosis of influenza infections and the investigation of influenza epidemiology.

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