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Review
. 1980 Feb;10(1):55-72.
doi: 10.1017/s003329170003960x.

The pathophysiology of extrapyramidal side-effects of neuroleptic drugs

Review

The pathophysiology of extrapyramidal side-effects of neuroleptic drugs

C D Marsden et al. Psychol Med. 1980 Feb.

Abstract

The mechanisms responsible for the production of major extrapyramidal side-effects (parkinsonism, akathisia, acute dystonic reactions, chronic tardive dyskinesias) are reviewed in the light of the complex effects of these drugs on cerebral dopamine systems.

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