The pathophysiology of extrapyramidal side-effects of neuroleptic drugs
- PMID: 6104342
- DOI: 10.1017/s003329170003960x
The pathophysiology of extrapyramidal side-effects of neuroleptic drugs
Abstract
The mechanisms responsible for the production of major extrapyramidal side-effects (parkinsonism, akathisia, acute dystonic reactions, chronic tardive dyskinesias) are reviewed in the light of the complex effects of these drugs on cerebral dopamine systems.