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Clinical Trial
. 1980 Jul 26;2(8187):180-2.
doi: 10.1016/s0140-6736(80)90063-x.

Propranolol--a medical treatment for portal hypertension?

D Lebrec, O Nouel, M Corbic, J P Benhamou
Clinical Trial

Propranolol--a medical treatment for portal hypertension?

D Lebrec et al. Lancet. .

Abstract

Continuous, oral administration of propranolol at doses which reduced the heart-rate by 25% produced a sustained decrease in portal venous pressure in cirrhotic patients with portal hypertension. This effect of propranolol might be useful in preventing recurrent bleeding due to ruptured oesophageal varices in patients with portal hypertension.

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