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Case Reports
. 1980 Aug 9;2(8189):292-4.
doi: 10.1016/s0140-6736(80)90237-8.

Treatment of acute respiratory failure with low-frequency positive-pressure ventilation and extracorporeal removal of CO2

L Gattinoni, A Agostoni, A Pesenti, A Pelizzola, G P Rossi, M Langer, S Vesconi, L Uziel, U Fox, F Longoni, T Kolobow, G Damia
Case Reports

Treatment of acute respiratory failure with low-frequency positive-pressure ventilation and extracorporeal removal of CO2

L Gattinoni et al. Lancet. .

Abstract

Terminal respiratory failure was reversed in three patients with a combination of extra-corporeal CO2 removal through a membrane lung and oxygen diffusion into the diseased lungs between mechanical breaths induced at a frequency of 2-3/min. The technique seems to prevent the pulmonary barotrauma and extrapulmonary derangements caused by conventional mechanical ventilation.

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