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. 1980 Aug;77(8):4564-8.
doi: 10.1073/pnas.77.8.4564.

gamma-Glutamylamine cyclotransferase: specificity toward epsilon-(L-gamma-glutamyl)-L-lysine and related compounds

M L Fink, S I Chung, J E Folk

gamma-Glutamylamine cyclotransferase: specificity toward epsilon-(L-gamma-glutamyl)-L-lysine and related compounds

M L Fink et al. Proc Natl Acad Sci U S A. 1980 Aug.

Abstract

gamma-Glutamylamine cyclotransferase, an enzyme that catalyzes the conversion of L-gamma-glutamylamines to free amines and 5-oxo-L-proline, was found in rabbit kidney and in various other tissues. The specificity of this enzyme indicates that it functions in the metabolism of products of transglutaminase action; among its substrates are epsilon-(L-gamma-glutamyl)-L-lysine, a derivative of this peptide in which the alpha-amino and carboxyl groups of the lysine moiety are blocked, and L-gamma-glutamyl-polyamine derivatives.

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References

    1. Biochemistry. 1966 Feb;5(2):665-73 - PubMed
    1. Biochem Biophys Res Commun. 1968 Feb 26;30(4):356-62 - PubMed
    1. Science. 1968 May 24;160(3830):892-3 - PubMed
    1. Biochemistry. 1969 Mar;8(3):1048-55 - PubMed
    1. J Biol Chem. 1969 Jul 10;244(13):3707-13 - PubMed

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