Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1981 Jan 8;109(1):83-9.
doi: 10.1016/0009-8981(81)90140-6.

Glycylprolyl-p-nitroanilidase in hepatobiliary disease

D R Hutchinson, R P Halliwell, J D Lockhart, D V Parke

Glycylprolyl-p-nitroanilidase in hepatobiliary disease

D R Hutchinson et al. Clin Chim Acta. .

Abstract

The serum activity of glycylprolyl-p-nitroanilidase (GPN) has been compared with isocitrate dehydrogenase and with alanine and aspartate aminotransferases in patients with hepatobiliary diseases, myocardial infarction and chronic inflammatory bowel disease. Serum GPN was markedly increased in all hepatobiliary diseases, especially secondary carcinoma and chronic alcoholic hepatitis, but no abnormal values were seen in patients with chronic inflammatory bowel disease. Slightly elevated GPN activities were noticed in a few cases of myocardial infarction. It is suggested that serum GPN would be useful for monitoring hepatic function, especially in the clinical trials of new drug.

PubMed Disclaimer

Publication types

MeSH terms

Substances

LinkOut - more resources