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. 1981 Mar 21;1(8221):636-8.
doi: 10.1016/s0140-6736(81)91554-3.

Successful tumour immunotherapy with cimetidine in mice

M E Osband, D Hamilton, Y J Shen, E Cohen, M Shlesinger, P Lavin, A Brown, R McCaffrey

Successful tumour immunotherapy with cimetidine in mice

M E Osband et al. Lancet. .

Abstract

Cimetidine significantly slowed metastatic development and prolonged survival in tumour-bearing mice, in association with inactivation of suppressor cells. Pharmacological blockade of the suppressor cell system may represent a new strategy for successful immunotherapy of human neoplasia.

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