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Clinical Trial
. 1980;15(5):281-91.
doi: 10.1159/000468451.

A controlled trial of oxypertine in tardive dyskinesia

H L Freeman, S D Soni, L Carpenter
Clinical Trial

A controlled trial of oxypertine in tardive dyskinesia

H L Freeman et al. Int Pharmacopsychiatry. 1980.

Abstract

A study was undertaken to investigate the effects of oxypertine in treating tardive dyskinesia. The design was double-blind, placebo-controlled, between-patient, in 28 patients from whom previous medication was withdrawn, with 14 patients in each group. Treatment was for 4 weeks. Although more oxypertine patients improved than placebo, i.e. 71.4 vs. 50%, the results did not reach statistically significant difference. A further study is planned to increase the overall number of patients in the study, and to lengthen treatment periods.

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