Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1981 Jun;18(6):663-78.
doi: 10.3109/15563658108990293.

Human xylazine overdose: a comparative review with clonidine, phenothiazines, and tricyclic antidepressants

A G Gallanosa, D A Spyker, J R Shipe, D L Morris
Review

Human xylazine overdose: a comparative review with clonidine, phenothiazines, and tricyclic antidepressants

A G Gallanosa et al. Clin Toxicol. 1981 Jun.

Abstract

We report a case of horse tranquilizer (xylazine) overdose from oral ingestion in man, detail a gas-liquid chromatography/mass spectrometer method for xylazine assay in the blood and urine, and suggest the management of acute poisoning. We present a comparative review of some toxicological properties that xylazine shares with the pharmacologically related clonidine and with the structurally related phenothiazines and the tricyclic antidepressants.

PubMed Disclaimer