doi: 10.1177/019459988108900629.
Electrophysiologic evidence for involvement of acetylcholine as a neurotransmitter in the lateral vestibular nucleus
- PMID: 6121314
- DOI: 10.1177/019459988108900629
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Electrophysiologic evidence for involvement of acetylcholine as a neurotransmitter in the lateral vestibular nucleus
Otolaryngol Head Neck Surg.
1981 Nov-Dec.
Abstract
Monosynaptic spike generation of lateral vestibular nucleus (LVN) neurons with vestibular nerve stimulation in cats was inhibited by microiontophoretic atropine and gamma-aminobutyric acid (GABA). Spontaneous firing of the LVN monosynaptic neuron was increased by iontophoretic acetylcholine and glutamate. Atropine inhibited acetylcholine-induced firing without affecting glutamate-induced firing, while GABA blocked spike generation produced by acetylcholine and glutamate. Acetylcholine probably plays a role in transmission from the vestibular nerve to the LVN monosynaptic neurons.
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