Induction of cytosolic tyrosine aminotransferase by dexamethasone in organ culture of fetal human liver
- PMID: 6124417
- DOI: 10.1016/0378-3782(82)90104-9
Induction of cytosolic tyrosine aminotransferase by dexamethasone in organ culture of fetal human liver
Abstract
Total tyrosine aminotransferase activity in organ culture of fetal human liver is increased by 347% after 15 h incubation with 2 micro M of dexamethasone. Isoelectric focusing reveals that the increased activity is due to induction of cytosolic tyrosine aminotransferase (EC 2.6.1.5) while the activity of the nonspecific mitochondrial aspartate aminotransferase (EC 2.6.1.1) remains unchanged.
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