Comparative Study
doi: 10.1007/BF00710685.
Neurotransmitter-synthesizing enzymes in 14 human neuroblastoma cell lines
- PMID: 6125265
- PMCID: PMC11572894
- DOI: 10.1007/BF00710685
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Comparative Study
Neurotransmitter-synthesizing enzymes in 14 human neuroblastoma cell lines
Cell Mol Neurobiol.
1981 Sep.
Abstract
Fourteen human neuroblastoma cell lines were studied for expression and regulation of neurotransmitter-synthesizing enzymes. All cell lines contained activities of adrenergic and/or cholinergic neurons and 13 expressed activities for both. None contained enzymes for serotonergic or GABAergic neurons. Enzyme activity was characteristic for a given cell line. Enzyme activity in cell lines was sensitive to growth phase, culture medium, and concentration of fetal bovine serum.
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