[T-lymphocyte subpopulations in mice: their respective role in the regulation of isotype expression]

Abstract

In this brief review the properties of some lymphocyte surface antigens are described. The biochemical characteristic and the cell distribution of the Lyt antigen are analysed. A peculiar consideration has also been devoted to a new family of T-cell alloantigens linked to Igh-1 and recently described by Owen et al. The respective role of T helper and T suppressor cells in the regulation of isotype expression is discussed in the light of data recently obtained in the laboratory.