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Comparative Study
. 1983;74(1):173-5.
doi: 10.1016/0742-8413(83)90170-6.

Hepatic microsomal O-de-ethylases in cod (Gadus morhua): their induction by Aroclor 1254 but not by Aroclor 1016

P D Hansen, R F Addison, D E Willis
Comparative Study

Hepatic microsomal O-de-ethylases in cod (Gadus morhua): their induction by Aroclor 1254 but not by Aroclor 1016

P D Hansen et al. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1983.

Abstract

1. The characteristics of hepatic ethoxycoumarin and ethoxyresorufin O-de-ethylases in juvenile cod (Gadus morhua) from the North Sea are described. 2. Feeding Aroclor 1254 to juvenile cod to produce liver concentrations of approx 900 microgram X g-1 (wet wt) induced ethoxycoumarin O-de-ethylase approx 30-fold, but had no effect on ethoxyresorufin O-deethylase activity. 3. Feeding Aroclor 1016 to juvenile cod to produce liver concentrations of approx 300 micrograms X g-1 (wet wt.) did not induce ethoxycoumarin O-de-ethylase activity.

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