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Case Reports
. 1983 Feb;21(1):89-93.
doi: 10.1016/0020-7292(83)90076-0.

Methoxyflurane hepatitis: two cases following obstetric analgesia

J E Delia, W S Maxson, J L Breen
Case Reports

Methoxyflurane hepatitis: two cases following obstetric analgesia

J E Delia et al. Int J Gynaecol Obstet. 1983 Feb.

Abstract

Methoxyflurane is utilized in obstetrics for analgesia during labor. It has been recognized as an unpredictable hepatotoxin. Although hepatitis has been seen after its use in anesthesia, only one case of hepatitis has been reported after its use for analgesia in labor. Two more cases of hepatitis following methoxyflurane analgesia are reported. Direct toxic effects of its metabolites and host idiosyncrasy may underlie the hepatic injury from methoxyflurane.

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