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. 1983 Jul 22;218(1213):481-4.
doi: 10.1098/rspb.1983.0053.

Recording of single gamma-aminobutyrate- and acetylcholine-activated receptor channels translated by exogenous mRNA in Xenopus oocytes

R Miledi, I Parker, K Sumikawa

Recording of single gamma-aminobutyrate- and acetylcholine-activated receptor channels translated by exogenous mRNA in Xenopus oocytes

R Miledi et al. Proc R Soc Lond B Biol Sci. .

Abstract

High resolution ('giga-seal') patch clamp recording in Xenopus oocytes was used to measure single channel currents from ACh- and GABA-activated receptors. The proteins that make up these receptors had been translated from mRNA derived from, respectively, denervated cat muscle and chick optic lobe.

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