[Immunological and zooparasitological characteristics of epizootics of hemorrhagic fever with renal syndrome in natural foci in the Amur River region]

Abstract

In natural foci of hemorrhagic fever with renal syndrome (HFRS) located in agricultural landscapes, rodents of various species are infected with the virus, however, regular HFRS epizootics are observed in field mice which present the highest abundance of infected animals in the population. Annually, a high direct correlation is observed between the population density of rodents and the percentage of animals with HFRS virus antigen in the blood and lungs. In 1981, there was a high correlation between the occurrence of rodents with Gamasid mites and the presence of the antigen in the blood. All the foregoing suggests that HFRS agent exists in natural foci due to a combination of different transmission mechanisms (obligate-transmissive mechanism) and penetrates into murine rodents by various modes: air--dust-borne and/or alimentary and transmissive. Non-transmissive modes are likely to be the leading ones.