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. 1983 Nov 15;39(11):1284-6.
doi: 10.1007/BF01990372.

Negative inotropic effect of some H2-receptor antagonists on the isolated human atria

Negative inotropic effect of some H2-receptor antagonists on the isolated human atria

G Coruzzi et al. Experientia. .

Abstract

H2-Receptor antagonists were found to possess in various degrees a negative inotropic effect on human atria in vitro. This effect seemed to be independent of H2-receptor blockade and, at least in the case of oxmetidine, seemed to involve calcium ion transport and/or utilization.

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