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. 1984 Feb 11;1(8372):305-7.
doi: 10.1016/s0140-6736(84)90359-3.

Enterotoxigenic Clostridium perfringens: a possible cause of antibiotic-associated diarrhoea

S P Borriello, H E Larson, A R Welch, F Barclay, M F Stringer, B A Bartholomew

Enterotoxigenic Clostridium perfringens: a possible cause of antibiotic-associated diarrhoea

S P Borriello et al. Lancet. .

Abstract

Free Clostridium perfringens enterotoxin was detected in the stools of 11 patients with diarrhoea. All had high faecal counts of enterotoxigenic strains of C perfringens, mostly of serotypes not commonly associated with food poisoning. 10 of these 11 patients had severe or prolonged diarrhoea which had developed after antibiotic treatment. Enterotoxigenic C perfringens appears to be one of the causes of antibiotic-associated diarrhoea.

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