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Clinical Trial
. 1984 Feb;6(1):27-31.

Desensitization to sulfasalazine after hypersensitivity reactions in patients with inflammatory bowel disease

B I Korelitz, D H Present, P H Rubin, S E Fochios
  • PMID: 6142067
Clinical Trial

Desensitization to sulfasalazine after hypersensitivity reactions in patients with inflammatory bowel disease

B I Korelitz et al. J Clin Gastroenterol. 1984 Feb.

Abstract

Desensitization to sulfasalazine was successful in 40/47 (85%) patients with IBD who previously had hypersensitivity reactions. The desensitization with sulfasalazine was well-tolerated with no serious complications in short- or long-term follow-up. The course of IBD was subsequently favorable in 35/40 (87%) for extended periods including 17/17 (100%) with ulcerative colitis. Desensitization should be attempted in patients who have had typical hypersensitivity reactions to sulfasalazine.

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