Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1984 Mar 10;1(8376):525-8.
doi: 10.1016/s0140-6736(84)90929-2.

Analysis of clinical specimens by hybridisation with probe containing repetitive DNA from Plasmodium falciparum. A novel approach to malaria diagnosis

L Franzén, G Westin, R Shabo, L Aslund, H Perlmann, T Persson, H Wigzell, U Pettersson

Analysis of clinical specimens by hybridisation with probe containing repetitive DNA from Plasmodium falciparum. A novel approach to malaria diagnosis

L Franzén et al. Lancet. .

Abstract

The capacity of a DNA probe containing cloned repetitive sequences from Plasmodium falciparum to identify malaria-infected blood samples was tested with a spot hybridisation assay. Parasitaemia levels of 0.001% could be detected in 50 microliters blood from patients. The probe correctly diagnosed P falciparum infection in patients from different continents and appeared to be specific for P falciparum, since it did not cross-react with three other Plasmodium species tested.

PubMed Disclaimer

Publication types

LinkOut - more resources