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Review
. 1984;58(1-2):9-35.
doi: 10.1007/BF00240602.

Transglutaminases

L Lorand, S M Conrad
Review

Transglutaminases

L Lorand et al. Mol Cell Biochem. 1984.

Abstract

This paper is intended as a background to the topic of transglutaminases, while focusing on current ideas regarding the biological roles of these enzymes. Specifically, the following topics are discussed: geometry of forming gamma-glutamyl-epsilon-lysine cross-linked structures; energetic considerations; the gamma-glutamyl-epsilon-lysine cross-link; amine incorporation assays; artefactual incorporation of amines in cells and tissue homogenates; synthetic substrate systems; regulation of transglutaminase activities; strategies for probing transglutaminase-mediated events in biological systems; the blood clotting paradigm; transglutaminase and cell aging: the Ca2+-enriched human erythrocyte; transglutaminase and cell activation: the thrombin-stimulated human platelet and the fertilized sea urchin egg.

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References

    1. Biochemistry. 1966 May;5(5):1747-53 - PubMed
    1. J Biol Chem. 1977 Jun 10;252(11):3752-9 - PubMed
    1. Anal Biochem. 1971 Nov;44(1):221-31 - PubMed
    1. Biochem Biophys Res Commun. 1973 May 1;52(1):51-6 - PubMed
    1. Arch Biochem Biophys. 1979 Nov;198(1):164-74 - PubMed

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