The risk/benefit ratio of depot neuroleptics: a Scandinavian perspective
- PMID: 6143744
Item in Clipboard
The risk/benefit ratio of depot neuroleptics: a Scandinavian perspective
J Clin Psychiatry.
1984 May.
Abstract
The three developmental phases in the acceptance and use of depot neuroleptics are described. The practical advantages of these drugs are considered, as well as the extrapyramidal side effects that may result from oral or depot administration. Local (injection site) and other side effects of depot neuroleptics are discussed. Typical plasma drug concentration curves and receptor responses of depot neuroleptics are illustrated. Alternative use of oral drugs and strategies to increase the effectiveness of depot forms are presented. The depot neuroleptics used in Scandinavia today are discussed, and predictions are made regarding their use in the future.
Similar articles
-
Depot fluphenazine: risk/benefit ratio.J Clin Psychiatry. 1984 May;45(5 Pt 2):28-35. J Clin Psychiatry. 1984. PMID: 6370986 Review.
-
Practical considerations in the use of depot neuroleptics for the treatment of schizophrenia.Br J Hosp Med. 1977 Jun;17(6):546-58. Br J Hosp Med. 1977. PMID: 18242 No abstract available.
-
Depot neuroleptics: side effects and safety.J Clin Psychopharmacol. 1986 Feb;6(1 Suppl):24S-29S. J Clin Psychopharmacol. 1986. PMID: 2870089 Review.
-
Depot neuroleptic therapy: an underutilized treatment option.J Clin Psychiatry. 1992 Dec;53(12):426-33. J Clin Psychiatry. 1992. PMID: 1362569 Review.
-
The use of depot neuroleptics: clinical experience in the United States.J Clin Psychiatry. 1984 May;45(5 Pt 2):5-12. J Clin Psychiatry. 1984. PMID: 6370987 Review.
Cited by
-
Long-acting risperidone compared with oral olanzapine and haloperidol depot in schizophrenia: a Belgian cost-effectiveness analysis.Pharmacoeconomics. 2005;23 Suppl 1:35-47. doi: 10.2165/00019053-200523001-00004. Pharmacoeconomics. 2005. PMID: 16416760
-
Perceptions and knowledge of antipsychotics among mental health professionals and patients.BJPsych Bull. 2017 Oct;41(5):254-259. doi: 10.1192/pb.bp.116.055483. BJPsych Bull. 2017. PMID: 29018549 Free PMC article.
-
Pharmacological treatment of patients with schizophrenia. Past and present problems and potential future therapy.Drugs. 1990 Apr;39(4):481-8. doi: 10.2165/00003495-199039040-00001. Drugs. 1990. PMID: 2190791 Review. No abstract available.
-
The role of long-acting injectable antipsychotics in schizophrenia: a critical appraisal.Ther Adv Psychopharmacol. 2014 Oct;4(5):198-219. doi: 10.1177/2045125314540297. Ther Adv Psychopharmacol. 2014. PMID: 25360245 Free PMC article. Review.
-
Comparative modelling of foetal exposure to maternal long-acting injectable versus oral daily antipsychotics.NPJ Womens Health. 2025;3(1):31. doi: 10.1038/s44294-025-00077-9. Epub 2025 May 15. NPJ Womens Health. 2025. PMID: 40386696 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Medical